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Details on Athanasopoulos Panagiotis:
|RUB Faculty, Institute||Faculty of Chemistry and Biochemistry|
|Type of Project||Research Stay|
|International Research Institution||Burke Medical Research Center-Weill Cornell Medical College|
|Location||White Plains, NY, USA|
|Report||During my PhD in Bochum, my work was focused on identifying sodium selenate (s.s) as a potential therapeutic target of Parkinson’s Disease (PD) through the activation of the Protein Phosphatase 2A (PP2A). A reason for that could be that PP2A has been shown by others to enhance the Ras pathway whose activation is neuroprotective for diseases such as PD and also Glaucoma. During my visit in US I was interested in investigating whether s.s could activate the Ras pathway locally in the eye region of glaucoma-mice models. Our initial data support this hypothesis and suggest that s.s. could be a chemical compound that could be potentially be used for glaucoma patient treatment.|