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Author |
|
| Name | Athanasopoulos , Panagiotis |
| Research field | / |
| Career stage | doctoral researcher |
| Home university/institution | Ruhr-Universität Bochum (RUB) |
| Department/Research unit at home university/institution | Chemistry and Biochemistry |
| Chair/Working group at home institution | / |
International activity |
|
| Country | United States |
| Location | White Plains, NY |
| University | / |
| Fund Research School | PR.INT |
| Type of activity | research stay |
| Period | No dates specified |
| Keywords | / |
| Report | During my PhD in Bochum, my work was focused on identifying sodium selenate (s.s) as a potential therapeutic target of Parkinson’s Disease (PD) through the activation of the Protein Phosphatase 2A (PP2A). A reason for that could be that PP2A has been shown by others to enhance the Ras pathway whose activation is neuroprotective for diseases such as PD and also Glaucoma. During my visit in US I was interested in investigating whether s.s could activate the Ras pathway locally in the eye region of glaucoma-mice models. Our initial data support this hypothesis and suggest that s.s. could be a chemical compound that could be potentially be used for glaucoma patient treatment. http://www.burke.org/research/faculty/23 |